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Karlsruhe ▸ Florence

Florence ▸ Karlsruhe ⇄
1 a dayfastest 14h15☾ 1 overnight busFlixBus🇩🇪 Germany → 🇮🇹 Italy

Direct buses · no change

KarlsruheStuttgartUlmBregenzMilanBolognaFlorence· 621 km as the crow flies
  • 20:10 → 10:25+1
    FlixBus N77 ☾ Overnight
    Karlsruhe central train station → Florence (Villa Costanza) · via Stuttgart, Ulm, Bregenz, Milan…
    14h155 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 20:10 → 09:25+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Karlsruhe to Florence?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Karlsruhe to Florence?

The fastest takes 14h15; the slowest 14h15, for 621 km as the crow flies.

Is there a night bus from Karlsruhe to Florence?

Yes: 1 overnight departure in the timetable, for example 20:10 arriving 10:25 the next morning.