Lyon to Florence bus: 4.7 a day, fastest 10h05

4.7 a dayfastest 10h05☾ 4 overnight busesBlaBlaCar Bus, FlixBus🇫🇷 France → 🇮🇹 Italy

Direct buses · no change

LyonChambéryTurinGenoaBolognaFlorence· 550 km as the crow flies

01:15 → 12:35
FlixBus N521 ☾ Overnight
Lyon (Gerland Bus Station) → Florence (Villa Costanza) · via Turin, Bologna
11h203 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 01:15 → 11:35)Book on FlixBus ↗
05:35 → 16:30
BlaBlaCar Bus
Lyon - Gerland Bus Station → Florence - Villa Constanza Bus Station · via Turin, Bologna
10h552 stops
Runs: Only Mon 26 Octthe open data has only these datesBook on BlaBlaCar Bus ↗
09:35 → 19:40
FlixBus 516
Lyon (Gerland Bus Station) → Florence (Villa Costanza) · via Turin, Genoa
10h052 stops
Runs: Mon, Tue, Fri, Sat, SunBook on FlixBus ↗
10:50 → 21:00
FlixBus 1501
Lyon (Gerland Bus Station) → Florence (Villa Costanza) · via Grenoble, Turin, Genoa
10h103 stops
Runs: DailyBook on FlixBus ↗
20:45 → 08:30⁺¹
FlixBus N580 ☾ Overnight
Lyon (Gerland Bus Station) → Florence (Villa Costanza) · via Chambéry, Turin, Genoa, Bologna
11h454 stops
Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 20:45 → 07:30+1)Book on FlixBus ↗
23:00 → 10:10⁺¹
FlixBus N527 ☾ Overnight
Lyon (Gerland Bus Station) → Florence (Villa Costanza) · via Chambéry, Turin, Milan, Bologna
11h104 stops
Runs: Daily except WedThe night the clocks change (Sat 24 Oct: 23:00 → 09:10+1)Book on FlixBus ↗
23:59 → 10:45⁺¹
BlaBlaCar Bus ☾ Overnight
Lyon - Gerland Bus Station → Florence - Villa Constanza Bus Station · via Turin, Milan, Bologna
10h463 stops
Runs: Mon, Sun (some weeks)The night the clocks change (Sat 24 Oct: 23:59 → 09:45+1)Book on BlaBlaCar Bus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

Fastest door to door: the plane (4h25). The bus takes 6h36 longer.

Bus · fastest direct11h01

To Lyon (Gerland Bus Station)17 min
At the stop before departure15 min
FlixBus 51610h05
From Florence (Villa Costanza)24 min

Plane · nonstop LYS to FLR4h25

To Lyon–Saint-Exupéry (LYS)50 min
Check-in & security1h30
Flight LYS to FLR1h25
Landing to exit20 min
From FLR20 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Lyon to Florence in pickthetrain's timetables: the bus is the no-change way.

Where Lyon goes by direct train ↗

Flying instead?

1 airline fly Lyon to Florence nonstop. Book on the airline's own site:

Volotea seasonalLYS→FLRBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Lyon to Florence?

Yes. 4.7 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Lyon to Florence?

The fastest takes 10h05; the slowest 11h45, for 550 km as the crow flies.

When do the buses leave?

The earliest leaves at 01:15 and the latest at 23:59, local time in Lyon. Not every bus runs every day: pick a date above.

Is there a night bus from Lyon to Florence?

Yes: 4 overnight departures in the timetable, for example 01:15 arriving 12:35.

Lyon ▸ Florence

Direct buses · no change

Quick answers

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