Lyon to Frankfurt bus: 3.4 a day, fastest 10h30

3.4 a dayfastest 10h30☾ 3 overnight busesBlaBlaCar Bus, FlixBus🇫🇷 France → 🇩🇪 Germany

Direct buses · no change

LyonGenevaLausanneBernBaselFreiburgFrankfurt· 563 km as the crow flies

02:05 → 13:20
BlaBlaCar Bus ☾ Overnight
Lyon - Gerland Bus Station → Frankfurt - Main Bus Station · via Nancy, Strasbourg, Karlsruhe, Darmstadt
11h155 stops
Runs: Mon, Thu (some weeks)Book on BlaBlaCar Bus ↗
02:20 → 12:50
FlixBus N235 ☾ Overnight
Lyon (Gerland Bus Station) → Frankfurt central train station · via Nancy, Metz, Saarbrücken
10h304 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 02:20 → 11:50)Book on FlixBus ↗
03:20 → 14:10
BlaBlaCar Bus
Lyon - Gerland Bus Station → Frankfurt - Main Bus Station · via Mulhouse, Colmar, Strasbourg, Karlsruhe…
10h506 stops
Runs: Tue, Sat, Sun (some weeks)The night the clocks change (Sun 25 Oct: 02:20 → 13:10)Book on BlaBlaCar Bus ↗
07:30 → 20:15
FlixBus 122
Lyon (Gerland Bus Station) → Frankfurt central train station · via Geneva, Lausanne, Bern, Basel…
12h457 stops
Runs: DailyBook on FlixBus ↗
23:00 → 10:45⁺¹
FlixBus N122 ☾ Overnight
Lyon (Gerland Bus Station) → Frankfurt central train station · via Geneva, Lausanne, Bern, Basel…
11h458 stops
Runs: Mon, Tue, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 23:00 → 09:45+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 02:20, arrive 12:50

The plane is 6h36 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct11h16

To Lyon (Gerland Bus Station)17 min
At the stop before departure15 min
FlixBus N23510h30
From Frankfurt central train station14 min

Train · fastest direct6h12

Before departure10 min
671A5h59
From Frankfurt(Main)Hbf3 min

Plane · nonstop LYS to FRA4h40

To Lyon–Saint-Exupéry (LYS)50 min
Check-in & security1h30
Flight LYS to FRA1h25
Landing to exit20 min
From FRA35 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance. Train: pickthetrain's door-to-door time.

Train instead?

5 a weekdirect trains, fastest 5h59

Société Nationale des Chemins de fer Français. No change of train, from the operators' official timetables.

See the trains on pickthetrain ↗

Flying instead?

2 airlines fly Lyon to Frankfurt nonstop. Book on the airline's own site:

Air DolomitiLYS→FRABook direct ↗
LufthansaLYS→FRABook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Lyon to Frankfurt?

Yes. 3.4 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Lyon to Frankfurt?

The fastest takes 10h30; the slowest 12h45, for 563 km as the crow flies.

When do the buses leave?

The earliest leaves at 02:05 and the latest at 23:00, local time in Lyon. Not every bus runs every day: pick a date above.

Is there a night bus from Lyon to Frankfurt?

Yes: 3 overnight departures in the timetable, for example 02:05 arriving 13:20.

Lyon ▸ Frankfurt

Direct buses · no change

Quick answers

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