Rome ▸ Zurich
Zurich ▸ Rome ⇄2 a dayfastest 12h05☾ 1 overnight busFlixBus🇮🇹 Italy → 🇨🇭 Switzerland
Direct buses · no change
RomeSienaBolognaMilanZurich· 685 km as the crow flies
- 09:25 → 21:40FlixBus 519Rome Tiburtina Bus station → Zurich Bus Station · via Siena, Bologna, Milan12h153 stopsRuns: DailyBook on FlixBus ↗
- 20:00 → 08:05+1FlixBus N524 ☾ OvernightRome Tiburtina Bus station → Zurich Bus Station · via Florence, Bologna, Milan12h054 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Rome to Zurich?
Yes. 2 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Rome to Zurich?
The fastest takes 12h05; the slowest 12h15, for 685 km as the crow flies.
When do the buses leave?
The earliest leaves at 09:25 and the latest at 20:00, local time in Rome. Not every bus runs every day: pick a date above.
Is there a night bus from Rome to Zurich?
Yes: 1 overnight departure in the timetable, for example 20:00 arriving 08:05 the next morning.