Prague to Lugano bus: 1 a day, fastest 11h10

1 a dayfastest 11h10☾ 1 overnight busFlixBus🇨🇿 Czechia → 🇨🇭 Switzerland

Direct buses · no change

PraguePlzeňRegensburgMunichChurLugano· 608 km as the crow flies

20:20 → 07:30⁺¹
FlixBus N1308 ☾ Overnight
Prague (Main Railway Station) → Lugano (Via Ciani) · via Plzeň, Regensburg, Munich, Chur
11h104 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 20:20 → 06:30+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 20:20, arrive 07:30

The plane is 6h50 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct11h50

To Prague (Main Railway Station)12 min
At the stop before departure15 min
FlixBus N130811h10
From Lugano (Via Ciani)13 min

Plane · nonstop PRG to MXP5h00

To Václav Havel Airport Prague (PRG)35 min
Check-in & security1h30
Flight PRG to MXP1h35
Landing to exit20 min
From MXP1h00

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Prague to Lugano in pickthetrain's timetables: the bus is the no-change way.

Where Prague goes by direct train ↗

Flying instead?

1 airline fly Prague to Lugano nonstop. Book on the airline's own site:

easyJetPRG→MXPBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Prague to Lugano?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Prague to Lugano?

The fastest takes 11h10; the slowest 11h10, for 608 km as the crow flies.

Is there a night bus from Prague to Lugano?

Yes: 1 overnight departure in the timetable, for example 20:20 arriving 07:30 the next morning.

Prague ▸ Lugano

Direct buses · no change

Quick answers

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