Lugano to Prague bus: 1 a day, fastest 11h35

1 a dayfastest 11h35☾ 1 overnight busFlixBus🇨🇭 Switzerland → 🇨🇿 Czechia

Direct buses · no change

LuganoChurMunichRegensburgPlzeňPrague· 608 km as the crow flies

23:00 → 10:35⁺¹
FlixBus N1308 ☾ Overnight
Lugano (Via Ciani) → Prague (Main Railway Station) · via Chur, Munich, Regensburg, Plzeň
11h354 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 23:00 → 09:35+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 23:00, arrive 10:35

The plane is 7h16 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct12h16

To Lugano (Via Ciani)13 min
At the stop before departure15 min
FlixBus N130811h35
From Prague (Main Railway Station)13 min

Plane · nonstop MXP to PRG5h00

To Milan Malpensa (MXP)1h00
Check-in & security1h30
Flight MXP to PRG1h35
Landing to exit20 min
From PRG35 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Lugano to Prague in pickthetrain's timetables: the bus is the no-change way.

Where Lugano goes by direct train ↗

Flying instead?

1 airline fly Lugano to Prague nonstop. Book on the airline's own site:

easyJetMXP→PRGBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Lugano to Prague?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Lugano to Prague?

The fastest takes 11h35; the slowest 11h35, for 608 km as the crow flies.

Is there a night bus from Lugano to Prague?

Yes: 1 overnight departure in the timetable, for example 23:00 arriving 10:35 the next morning.

Lugano ▸ Prague

Direct buses · no change

Quick answers

More from Lugano

More to Prague