Milan ▸ Plzeň
Plzeň ▸ Milan ⇄1 a dayfastest 11h50☾ 1 overnight busFlixBus🇮🇹 Italy → 🇨🇿 Czechia
Direct buses · no change
MilanComoLuganoChurMunichRegensburgPlzeň· 570 km as the crow flies
- 21:10 → 09:00+1FlixBus N1308 ☾ OvernightMilan (Lampugnano bus station) → Plzeň (central bus station) · via Como, Lugano, Chur, Munich…11h505 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Milan to Plzeň?
Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Milan to Plzeň?
The fastest takes 11h50; the slowest 11h50, for 570 km as the crow flies.
Is there a night bus from Milan to Plzeň?
Yes: 1 overnight departure in the timetable, for example 21:10 arriving 09:00 the next morning.