Mulhouse to Prague bus: 2.7 a day, fastest 9h26

2.7 a dayfastest 9h26☾ 3 overnight busesFlixBus🇫🇷 France → 🇨🇿 Czechia

Direct buses · no change

MulhouseColmarStrasbourgKarlsruheStuttgartHeilbronnPrague· 579 km as the crow flies

03:00 → 15:25
FlixBus N1315 ☾ Overnight
Mulhouse (bus station) → Prague (Central Bus Station Florenc) · via Colmar, Strasbourg, Karlsruhe, Stuttgart…
12h2511 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 02:00 → 14:25)Book on FlixBus ↗
18:05 → 07:00⁺¹
FlixBus N199 ☾ Overnight
Mulhouse (bus station) → Prague (Main Railway Station) · via Saint-Louis, Basel, Zurich, Munich…
12h558 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 18:05 → 06:00+1)Book on FlixBus ↗
23:54 → 09:20⁺¹
FlixBus N1759 ☾ Overnight
Mulhouse (bus station) → Prague (Central Bus Station Florenc) · via Freiburg, Nuremberg
9h263 stops
Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 23:54 → 08:20+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 23:54, arrive 09:20

The plane is 5h12 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct10h07

To Mulhouse (bus station)13 min
At the stop before departure15 min
FlixBus N17599h26
From Prague (Central Bus Station Florenc)13 min

Plane · nonstop BSL to PRG4h55

To EuroAirport Basel–Mulhouse–Freiburg (BSL)1h00
Check-in & security1h30
Flight BSL to PRG1h30
Landing to exit20 min
From PRG35 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Mulhouse to Prague in pickthetrain's timetables: the bus is the no-change way.

Where Mulhouse goes by direct train ↗

Flying instead?

1 airline fly Mulhouse to Prague nonstop. Book on the airline's own site:

easyJetBSL→PRGBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Mulhouse to Prague?

Yes. 2.7 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Mulhouse to Prague?

The fastest takes 9h26; the slowest 12h55, for 579 km as the crow flies.

When do the buses leave?

The earliest leaves at 03:00 and the latest at 23:54, local time in Mulhouse. Not every bus runs every day: pick a date above.

Is there a night bus from Mulhouse to Prague?

Yes: 3 overnight departures in the timetable, for example 03:00 arriving 15:25.

Mulhouse ▸ Prague

Direct buses · no change

Quick answers

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