Mestre ▸ Frankfurt
Frankfurt ▸ Mestre ⇄2.4 a dayfastest 12h25☾ 3 overnight busesFlixBus🇮🇹 Italy → 🇩🇪 Germany
Direct buses · no change
MestreVeniceVeronaTrentoBolzanoMunichFrankfurt· 579 km as the crow flies
- 16:45 → 08:10+1FlixBus N277 ☾ OvernightVenice (Marco Polo Airport) → Frankfurt central train station · via Venice, Verona, Trento, Bolzano…15h2513 stopsRuns: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 16:45 → 07:10+1)Book on FlixBus ↗
- 17:40 → 08:10+1FlixBus N277 ☾ OvernightVenice Mestre (Stazione FS) → Frankfurt central train station · via Verona, Trento, Bolzano, Munich…14h3011 stopsRuns: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 17:40 → 07:10+1)Book on FlixBus ↗
- 21:20 → 09:45+1FlixBus N28 ☾ OvernightVenice Mestre (Stazione FS) → Frankfurt Airport (P36, Terminal 1) · via Verona, Munich, Nuremberg12h253 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Mestre to Frankfurt?
Yes. 2.4 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Mestre to Frankfurt?
The fastest takes 12h25; the slowest 15h25, for 579 km as the crow flies.
When do the buses leave?
The earliest leaves at 16:45 and the latest at 21:20, local time in Mestre. Not every bus runs every day: pick a date above.
Is there a night bus from Mestre to Frankfurt?
Yes: 3 overnight departures in the timetable, for example 16:45 arriving 08:10 the next morning.