pickthebus

Heidelberg ▸ Prague

Prague ▸ Heidelberg ⇄
2.3 a dayfastest 6h50☾ 1 overnight busBlaBlaCar Bus, FlixBus🇩🇪 Germany → 🇨🇿 Czechia

Direct buses · no change

HeidelbergNeckarsulmWolpertshausenNurembergPrague· 418 km as the crow flies
  • 02:55 → 09:45
    BlaBlaCar Bus ☾ Overnight
    Heidelberg → Prague - Florenc Main Bus Terminal · via Nuremberg
    6h501 stop
    Runs: Tue, Sat (some weeks)Book on BlaBlaCar Bus ↗
  • 05:44 → 13:05
    FlixBus N109
    Heidelberg Pre Waypoint → Prague (Central Bus Station Florenc) · via Neckarsulm, Wolpertshausen, Nuremberg
    7h216 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 04:44 → 12:05)Book on FlixBus ↗
  • 15:59 → 23:10
    FlixBus 109
    Heidelberg Pre Waypoint → Prague (Central Bus Station Florenc) · via Wolpertshausen, Nuremberg
    7h115 stops
    Runs: Mon to FriBook on FlixBus ↗
  • 16:09 → 23:10
    FlixBus 109
    Heidelberg Pre Waypoint → Prague (Central Bus Station Florenc) · via Wolpertshausen, Nuremberg
    7h015 stops
    Runs: Sat, SunBook on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Heidelberg to Prague?

Yes. 2.3 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Heidelberg to Prague?

The fastest takes 6h50; the slowest 7h21, for 418 km as the crow flies.

When do the buses leave?

The earliest leaves at 02:55 and the latest at 16:09, local time in Heidelberg. Not every bus runs every day: pick a date above.

Is there a night bus from Heidelberg to Prague?

Yes: 1 overnight departure in the timetable, for example 02:55 arriving 09:45.