Heidelberg ▸ Prague
Prague ▸ Heidelberg ⇄Direct buses · no change
- 02:55 → 09:45BlaBlaCar Bus ☾ OvernightHeidelberg → Prague - Florenc Main Bus Terminal · via Nuremberg6h501 stopRuns: Tue, Sat (some weeks)Book on BlaBlaCar Bus ↗
- 05:44 → 13:05FlixBus N109Heidelberg Pre Waypoint → Prague (Central Bus Station Florenc) · via Neckarsulm, Wolpertshausen, Nuremberg7h216 stops
- 15:59 → 23:10FlixBus 109Heidelberg Pre Waypoint → Prague (Central Bus Station Florenc) · via Wolpertshausen, Nuremberg7h115 stopsRuns: Mon to FriBook on FlixBus ↗
- 16:09 → 23:10FlixBus 109Heidelberg Pre Waypoint → Prague (Central Bus Station Florenc) · via Wolpertshausen, Nuremberg7h015 stopsRuns: Sat, SunBook on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Heidelberg to Prague?
Yes. 2.3 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Heidelberg to Prague?
The fastest takes 6h50; the slowest 7h21, for 418 km as the crow flies.
When do the buses leave?
The earliest leaves at 02:55 and the latest at 16:09, local time in Heidelberg. Not every bus runs every day: pick a date above.
Is there a night bus from Heidelberg to Prague?
Yes: 1 overnight departure in the timetable, for example 02:55 arriving 09:45.