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Frankfurt ▸ Prague

Prague ▸ Frankfurt ⇄
6.3 a dayfastest 6h56☾ 1 overnight busFlixBus🇩🇪 Germany → 🇨🇿 Czechia

Direct buses · no change

FrankfurtWürzburgSchweinfurtBambergBayreuthBischofsgrünPrague· 409 km as the crow flies
  • 06:05 → 13:30
    FlixBus N84
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Erlangen, Nuremberg
    7h252 stops
    Runs: Daily until Mon 2 NovThe night the clocks change (Sun 25 Oct: 05:05 → 12:30)Book on FlixBus ↗
  • 09:00 → 17:55
    FlixBus 068
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Würzburg, Schweinfurt, Bamberg, Bayreuth…
    8h559 stops
    Runs: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
  • 11:15 → 19:35
    FlixBus 084
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Wertheim, Würzburg, Nuremberg, Plzeň
    8h205 stops
  • 13:00 → 21:30
    FlixBus 084
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Würzburg, Erlangen, Nuremberg
    8h304 stops
    Runs: Daily until Sat 14 Nov, not Mon 9 Nov, Tue 10 Nov, Wed 11 NovBook on FlixBus ↗
  • 13:45 → 20:45
    FlixBus N870
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Nuremberg
    7h001 stop
    Runs: Only Sat 7 Novthe open data has only these datesBook on FlixBus ↗
  • 14:00 → 21:00
    FlixBus N870
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Nuremberg
    7h001 stop
    Runs: Only Mon 9 Novthe open data has only these datesBook on FlixBus ↗
  • 14:23 → 21:23
    FlixBus N870
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Nuremberg
    7h001 stop
    Runs: Only Sun 8 Novthe open data has only these datesBook on FlixBus ↗
  • 14:30 → 21:30
    FlixBus N870
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Nuremberg
    7h001 stop
    Runs: Tue to Fri (some weeks)Book on FlixBus ↗
  • 15:30 → 22:30
    FlixBus N870
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Nuremberg
    7h001 stop
    Runs: Only Sun 18 Octthe open data has only these datesBook on FlixBus ↗
  • 15:50 → 22:50
    FlixBus N870
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Nuremberg
    7h001 stop
    Runs: Mon, Sat (some weeks)Book on FlixBus ↗
  • 17:20 → 00:45+1
    FlixBus N1310
    Frankfurt central train station → Prague (Main Railway Station) · via Erlangen, Nuremberg
    7h253 stops
  • 23:59 → 06:55+1
    FlixBus N84 ☾ Overnight
    Frankfurt central train station → Prague (Central Bus Station Florenc) · via Würzburg, Nuremberg
    6h562 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 23:59 → 05:55+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and FlixBus UK (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Frankfurt to Prague?

Yes. 6.3 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Frankfurt to Prague?

The fastest takes 6h56; the slowest 8h55, for 409 km as the crow flies.

When do the buses leave?

The earliest leaves at 06:05 and the latest at 23:59, local time in Frankfurt. Not every bus runs every day: pick a date above.

Is there a night bus from Frankfurt to Prague?

Yes: 1 overnight departure in the timetable, for example 23:59 arriving 06:55 the next morning.