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Avignon ▸ Prague

Prague ▸ Avignon ⇄
1 a dayfastest 20h25☾ 1 overnight busFlixBus🇫🇷 France → 🇨🇿 Czechia

Direct buses · no change

AvignonLyonChalon-sur-SaôneBelfortMulhouseColmarPrague· 997 km as the crow flies
  • 19:00 → 15:25+1
    FlixBus N1315 ☾ Overnight
    Avignon (Le Pontet) → Prague (Central Bus Station Florenc) · via Lyon, Chalon-sur-Saône, Belfort, Mulhouse…
    20h2515 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 19:00 → 14:25+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Avignon to Prague?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Avignon to Prague?

The fastest takes 20h25; the slowest 20h25, for 997 km as the crow flies.

Is there a night bus from Avignon to Prague?

Yes: 1 overnight departure in the timetable, for example 19:00 arriving 15:25 the next morning.